1Jan

Tkp 45 201 111 2008 02250

Tkp 45 201 111 2008 02250 Rating: 4,1/5 7717 votes

ATG4D - Cysteine protease ATG4D; Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms; Belongs to the peptidase C54 family [a.k.a. APG4D, AUTL4, uc010dxj.4]. ATG4C - Cysteine protease ATG4C; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.

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Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy [.] [a.k.a. APG4C, AUTL1, AUTL3]. ATG4A - Cysteine protease ATG4A; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.

Nov 8, 2018 - 45, 9.000e-38, gi 808997788 ref WP_046291478.1 ferredoxin [Pandoraea. Subunit gamma [Rhodothermus marinus], clstr ali, 44, 201. 111, 8.000e-36, gi 524380004 emb CDB32727.1 putative. TKP], clstr ali, 30, 37. Ferredoxin [Lachnospiraceae bacterium YSB2008], clstr ali, 40, 12. NRRL S-475] #=GS WP_051715663.1/33-111 DE [subseq from] hypothetical protein. [Catalinimonas alkaloidigena] #=GS OFX56583.1/45-179 DE [subseq from]. SDB] #=GS ABA55570.1/77-201 DE [subseq from] chloroplast stability factor. TKP] AOE68483.1 hypothetical protein A7317_16200 [Pseudomonas.

Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms [a.k.a. AUTL2, APG4A, ENSP8]. ATG4B - Cysteine protease ATG4B; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms [a.k.a.

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KIAA0943, AUTL1, APG4B]. TNFRSF1A - Tumor necrosis factor receptor superfamily member 1A; Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. Onekey recovery 70 engineering system. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase; CD molecules [a.k.a. TNFAR, TNFR1, A8K4X3]. TNFRSF10B - Tumor necrosis factor receptor superfamily member 10B; Receptor for the cytotoxic ligand TNFSF10/TRAIL.